Virginia Commonwealth University

Richmond, Va.

VCU Health Sciences

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Researchers identify mechanism used by therapeutically active antitumor cytokine gene able to induce potent bystander antitumor effect in cancer cells

Virginia Commonwealth University and VCU Massey Cancer Center researchers have uncovered how a gene, melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24), induces a bystander effect that kills cancer cells not directly receiving mda-7/IL-24 without harming healthy ones, a discovery that could lead to new therapeutic strategies to fight metastatic disease. Read more.